Many areas of the brain help you create and retrieve memories. A problem in any of these areas can lead to memory loss.
Normal aging can cause some forgetfulness. It is normal to have some trouble learning new material or needing more time to remember it. But normal aging does not lead to dramatic memory loss. Such memory loss is due to other diseases.
Memory loss may result from a new injury to the brain, which is caused by or is present after:
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Brain tumor
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Cancer treatment, such as brain radiation, bone marrow transplant, or chemotherapy
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Concussion or head trauma
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Not enough oxygen getting to the brain when your heart or breathing is stopped for too long
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Severe brain infection or infection around brain
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Major surgery or severe illness, including brain surgery
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Transient global amnesia (sudden, temporary loss of memory) of unclear cause
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Transient ischemic attack (TIA) or stroke
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Hydrocephalus (fluid collection in the brain)
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Multiple sclerosis
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Dementia
Sometimes, memory loss occurs with mental health problems, such as:
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After a major, traumatic or stressful event
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Bipolar disorder
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Depression or other mental health disorders, such as schizophrenia
Memory loss may be a sign of dementia. Dementia also affects thinking, language, judgment, and behavior. Common types of dementia associated with memory loss are:
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Alzheimer disease
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Vascular dementia
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Lewy body dementia
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Fronto-temporal dementia
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Progressive supranuclear palsy
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Normal pressure hydrocephalus
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Creutzfeldt-Jakob disease
Other causes of memory loss include:
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Alcohol or use of prescription or illegal drugs
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Brain infections such as Lyme disease, syphilis, or HIV/AIDS
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Overuse of medicines, such as barbiturates or (hypnotics)
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ECT (electroconvulsive therapy) (most often short-term memory loss)
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Epilepsy that is not well controlled
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Illness that results in the loss of, or damage to brain tissue or nerve cells, such as Parkinson disease, Huntington disease, or multiple sclerosis
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Low levels of important nutrients or vitamins, such as low vitamin B1 or B12
Memory loss is unusual forgetfulness. You may not be able to remember new events, recall one or more memories of the past, or both. The memory loss may be for a short time and then resolve (transient). Or, it may not go away, and, depending on the cause, it can get worse over time.
Alternative Names:
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Forgetfulness
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Amnesia
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Impaired memory
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Loss of memory
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Amnestic syndrome
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Dementia - memory loss
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Mild cognitive impairment - memory loss
To properly diagnose memory loss, your health care provider will perform a physical exam and ask about symptoms and medical history. This will usually also include asking questions of family members and friends and they may be interviewed in-person or by phone.
Medical history questions may address:
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Type of memory loss, such as short-term or long-term
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Time pattern, such as how long the memory loss has lasted or whether it comes and goes
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Things that triggered memory loss, such as head injury or surgery
Tests that may be done include:
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Blood tests for specific diseases that are suspected (such as low vitamin B12 or thyroid disease)
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Cerebral angiography
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Cognitive tests (neuropsychological/psychometric tests)
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CT scan or MRI of the head
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EEG
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Lumbar puncture